Low Testosterone in New Type 2 Diabetics.

This study investigates the testosterone levels in men with early-onset type 2 diabetes (T2DM) and compares them to those with late-onset T2DM. The results show that men with early-onset T2DM have lower serum total testosterone (TT), sex hormone-binding globulin (SHBG), and FSH levels, but higher dehydroepiandrosterone sulfate (DHEA-S) levels compared to men with late-onset T2DM. The decreased TT levels in patients with early-onset T2DM are associated with higher HbA1c, BMI, and triglyceride levels. The study also found that early-onset T2DM patients had a lower 3β-HSD concentration, which is essential for the conversion of DHEA to testosterone. This suggests that the low testosterone levels in these patients may be due to the low level of 3β-HSD and high blood glucose. In conclusion, men with early-onset T2DM have lower TT levels, and this condition requires aggressive treatment to address poor glycemic control, obesity, lipid disorder, and testosterone deficiency.

Hu, Y. et al.  2023.  Journal of Diabetes Research.  Low Total Testosterone Levels in Men with Newly Diagnosed Early-Onset Type 2 Diabetes: A Cross-Sectional Study in China.  Volume 2023 | Article ID 2082940 | https://doi.org/10.1155/2023/2082940

So, high levels of sugar seem to prevent the conversion of DHEA to Testosterone.  Well, then should we lower sugar intake or add Testosterone?  We say, how about both! 

Jason & Rita