Effects of Hormone Replacement Therapy

Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomized trial. After 10 years of randomized treatment, women receiving hormone replacement therapy (estradiol) early after menopause had a significantly reduced risk of mortality, heart failure, or myocardial infarction, without any apparent increase in risk of cancer, venous thromboembolism, or stroke.

Effect of replacement therapy on cardiovascular events in recently postmenopausal women: randomized trial.  BMJ. Oct 2012. 345:e6409.